Shelly Fan. Volek, Jeff S. The protein-sparing modified fast PSMF is a human-engineered variation on natural starvation designed to extend the period of rapid weight loss and low hunger while preventing the body from catabolizing itself. Reported hair loss may be due to many other reasons, for example, starvation , which is often the case with extreme diets as severe caloric restriction with chronic starvation can also induce hair loss.
Given the methodological caveats mentioned earlier, it does not appear to work better in any particular type of patient. Kossoff et al. Abstract Obesity is reaching epidemic proportions and is a strong risk factor for a number of cardiovascular and metabolic disorders such as hypertension, type 2 diabetes, dyslipidemia, atherosclerosis, and also certain types of cancers.
In contrast to findings by Foster et al. One distinct advantage to the fasting phase is that it gives physicians and families the chance to observe the patient's reaction in a controlled environment, and a brief fast may be a therapeutic strategy to improve seizure control as an outpatient.
During the first comparison month, the subjects who consumed the PSMF lost significantly more weight and reported significantly less hunger than did the subjects who consumed the balanced diet; the former group reported significantly greater problems with cold intolerance, constipation, dizziness, dry skin, and fatigue.
The diet is discontinued for the following reasons: In summary, the ketogenic diet works in patients of all ages and seizure types in a variety of settings. Brehm, Bonnie J. The long-term effects of the low-carbohydrate diets on blood lipid profile give a mixed picture of positive and negative changes .
Growth height and weight may be impaired, an effect most noticed in younger children Vining et al. They were also evaluated after 12 months.
If only water is ingested, stores of liver glycogen decrease steadily to zero in the first 12—24 h 23. Low-carbohydrate diets tend to result in reduced intake of fibre and fruits, and increased intake of cholesterol and saturated fat, [8,9] all of which are risk factors for mortality and cardiovascular disease .
Last Updated: No conflicts of interest were reported. The good antiepileptic effect and a slight fall off in efficacy during the study could justify this.
Wycherley, Thomas Philip, et al. The ketogenic diet is a chronic therapy, however. Sleep disturbances are common in patients with epilepsy Mendez and Radtke, ; Bazil, A retrospective study showed that the diet has similar efficacy when used after zero or one medication has been tried i.
It is no surprise, therefore, to learn that peer-reviewed scientific studies continue to show that the high-fat ketogenic diet supports cognitive health and can help prevent or reduce cognitive diseases such as Alzheimer's.The Journal of Pediatrics, The Lancet Child & Adolescent Health, Gastroenterology, Journal of the American Academy of Dermatology, and The Journal of Allergy and Clinical Immunology are pleased to offer you Shared Science articles for free for a limited time.
The ketogenic diet (or keto diet) is basically a very low-carbohydrate, adequate/low-protein, high-fat diet. It forces the body to burn fats rather than carbohydrates. This diet is used (since ) in medicine to treat epilepsy and can, in some cases, completely remove the need for medication [1,2,3].
Summary: The ketogenic diet remains a valuable therapeutic option for patients with intractable epilepsy. Clinical aspects of the diet's success may provide insights into Cited by: ketogenic diet in the management of diab etes Tony David K, Divyanjali P, Sai Krishna G * Department of Pharmacy Practice, JSS College o f Pharmacy, JSS University, Mysore, Karnataka, India.
BMC Pediatrics is an open access journal publishing peer-reviewed research articles Indexed in PubMed · Author retains copyright · Open research for all. Stella Iacovides and Rebecca M. Meiring, The effect of a ketogenic diet versus a high-carbohydrate, low-fat diet on sleep, cognition, thyroid function, and cardiovascular health independent of weight loss: study protocol for a randomized controlled trial, Trials, 19, 1, ().Cited by: